NOW Supplements, L-Lysine (L-Lysine Hydrochloride) 500 mg, Amino Acid, 250 Tablets

(426 Reviews)

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$9.85

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(20000 available )

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98 Ratings
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  • Tim

    > 3 day

    My last cold sore breakout was 1.5 years ago. After then, I had started taking these supplements for the purpose of preventing future outbreaks. I typically experience a cold sore outbreak roughly once every six months but Ive been mostly clear with the exception of a short and very tame outbreak on my lower lip last week. Needless to say, Im happier now that I have less cold sore episodes. Its entirely possible that my improved condition and the use of this product are unrelated, but I choose to believe otherwise. I recommend taking this supplement daily if you experience cold sores.

  • MaggieD

    10-06-2025

    I didnt notice tablets (didnt even know it came in tablet form) so will not work for sprinkling on cat food. I will take it myself and get capsules for my cat. As for the L-Lysine, all my cats have loved it on their food. A vet recommended it years ago for respiratory and immune system support for my one purebred who came to me with an incurable respiratory condition which the vet expected would kill him (my cat, not the vet). He lived to be 14 - the oldest lived cat Ive ever had (except for his litter-mate brother who is still alive and in good health). Its impossible to know if the L-Lysine was directly responsible for his long life but it certainly didnt hurt.

  • Diana

    > 3 day

    not sure why, but the tablets dont seem to work as well as the capsules

  • kolea

    > 3 day

    Id rather swallow 2 500mg tablets like these than a larger 1000mg one. Theyre coated making them smoother.

  • I am ready

    > 3 day

    I usually get capsule and ordered these instead without reading....ouch. I hate big pills and often cut in half to get them down, but these I can swallow with no problem and they are the same good quality as I expected from NOW.

  • xochi718

    > 3 day

    Best value in Lysine.

  • Mallie Renner

    > 3 day

    Now always seems to work well.

  • Donald

    > 3 day

    Product is quality

  • Blue Dog

    Greater than one week

    I am incredibly prone to cold sores (especially during the start of a cycle - because yes Im that lucky.) I dont just get a tiny little cold sore thats a minor irritation. These suckers spread across my entire lip, they itch like mad crazy, blister like someone lit my face on fire and take a good 10+ days to heal. Then one of my friends mentioned that taking Lysine helps reduce the duration of time it takes for a cold sore to go away. So when Id get one, Id pound the lysine and sure enough, the cold sore would either go away or shrink down to a tiny little thing that was barely noticeable. Once I realized it was working, I decided to take Lysine regularly, and I no longer get cold sores. YAY!

  • TickleMePretty

    > 3 day

    This is my greatest tool in my arsenal whenever I start to get a cold sore. Reduces the severity and duration by like half! The pills are easy to swallow and the price is fair. I love the Now brand and will continue to purchase this product!

L-Lysine is an essential amino acid, which means that it cannot be manufactured by the body and must be obtained through the diet or by supplementation. Lysine is necessary for the production of all protein in the body including hormones, enzymes, and antibodies, as well as carnitine and collagen, which is the structural protein forming all connective tissue such as skin, tendon, and bone. L-Lysine also plays a major role in calcium absorption. Some evidence suggests that L-Lysine supplementation may help to support a healthy immune system as well as proper cardiovascular function.*

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